منابع مشابه
Numerical modeling of links behavior in eccentric bracings with dual vertical links
Configuration and geometry of bracing systems affect the seismic performance of structures significantly. Recently, the current authors have introduced a new configuration for eccentric bracing of structural frames that may be assumed as the combination of inverted Y-type and rotated K-type EBFs. The resulted braced frame is called EBF-DVL, consisting of two vertical links attached together by ...
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Our previous study has reported that superoxide mediates ischemia-reperfusion (IR)-induced necrosis in mouse skeletal muscle. However, it remains poorly understood whether IR induces apoptosis and what factors are involved in IR-induced apoptosis in skeletal muscle. Using a murine model of tourniquet-induced hindlimb IR, we investigated the relationship between mitochondrial dysfunction and apo...
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Circulating natriuretic peptide (NP) levels are reduced in obesity and predict the risk of type 2 diabetes (T2D). Since skeletal muscle was recently shown as a key target tissue of NP, we aimed to investigate muscle NP receptor (NPR) expression in the context of obesity and T2D. Muscle NPRA correlated positively with whole-body insulin sensitivity in humans and was strikingly downregulated in o...
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Skeletal muscle insulin resistance in type 2 diabetes is associated with a shift from oxidative to glycolytic metabolism in myofibers. However, whether this metabolic switch is detrimental or adaptive for metabolic homeostasis has not been resolved. We recently demonstrated that the Baf60c/Deptor pathway promotes glycolytic metabolism in the muscle and protects mice from diet-induced insulin re...
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ژورنال
عنوان ژورنال: Nature Reviews Cancer
سال: 2003
ISSN: 1474-175X,1474-1768
DOI: 10.1038/nrc1106